bioprocess engineering

O’Neal has a reputation for deep in-house expertise in bioprocess engineering since its inception. This knowledge base is built on decades of collective experience designing bioprocess facilities and equipment. So whether you’re working with a traditional cell culture or fermentation platform process, processing a BL2 live virus, or pioneering the development of tissue, cell or gene therapy, O’Neal speaks your language.

When you get right down to it, Bioprocess Technologyone of the biggest challenges with bioprocess unit operations is bioburden control. Every aspect of a manufacturing facility design – from floorplan, to utilities, to equipment –must take into account the need to protect the product from bioburden contamination. Ultimately, the need for technology to control, reduce, or eliminate bioburden is what sets bioprocessing apart—and O’Neal’s thought leadership in this area is undisputed. 

Our foundational knowledge of how bioprocess unit operations work; the ability to develop deep understanding of your entire process; expertise in hygienic design, bioburden control, and aseptic processing technology; and strong design capabilities supporting the integration of clean-in-place (CIP), steam-in-place (SIP), and single-use technologies. We set the standard for bioprocess engineering.  Regardless of your project needs, O’Neal stands ready to become your indispensable partner.

  • Cell Culture/Fermentation
  • Live Virus Production
  • Cell and Tissue Therapy
  • Gene Therapy
  • Perfusion Technology
  • Harvest
  • Media Preparation
  • Recovery
  • Purification
  • Polishing
  • Buffer Preparation
  • Viral Clearance
  • Formulation
  • Bulk Filling
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